Alopecia Areata

 

 

Alopecia Areata

Alopecia can be inherited, related to 
shock or stress, dietary deficiencies such as malnutrition, genetic disorders, medication, and an autoimmune disorder. 


Alopecia Areata is a type of hair loss that occurs   when immune system  mistakenly attacks hair follicles.



The hair loss usually  is  not permanent.

 
Biopsies of affected skin show immune lymphocytes penetrating into the hair bulb of the hair follicles. The autoimmune destruction in Alopecia Areata may be mediated in part by CD8 ⁺, NKG2D ⁺ ,cytotoxic T cells. 


Alopecia areata is occasionally associated with other autoimmune conditions such as allergic disorders, Thyroid disease, Vitiligo , lupus, Rheumatoid arthritis, and Ulcerative colitis.



One of my friend got this disease after he shocked by  bad news. In his hair and beard.  After six month, at first his hair grow in grey and then change to black.

Amos Gilhar, Amos Etzioni, and Ralf Paus. Alopecia Areata,N Engl J Med 2012;366:1515-25.