Friday, October 16, 2015

Histology



                                                                   
                                                              Ehlers-Danlos Syndrome 




          The Ehlers-Danlos syndrome is a genetic connective tissue disorder that affect blood vessels, skin, bone, ligaments, internal organ and teeth. It is supposed that 1 out of 5000 individuals suffer from Ehlers-Danlos syndrome throughout the world. The clinical symptoms varies from mild skin and joint dislocation to severe and life threatening vascular type. The most common form of Ehlers-Danlos syndrome (EDS) is characterized by hyper extensibility of skin, fragile tissue especially skin which causes easy bruising, poor wound healing and hyper mobility of joint which causes dislocation and joint pain. In addition, mutation in the collagen which is one of the principal components of connective tissue lead to Ehlers-Danlos syndrome. 

 There are six distinct types of EDS and the main reason for causing this syndrome in gene mutation in collagen type I, III and IV. 

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              There is no cure for Ehlers-Danlos syndrome but treatment manage manifestation and prevent further damage. By decreasing blood pressure, reduce the stress in vassal because of fragile blood vessels. Pain relievers ibuprofen and naproxen sodium can reduce joint pain. Furthermore, maybe surgery recommended for repairing joints damaged.





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