Friday, March 28, 2014


Crohn's disease 


:chronic inflammatory disease of the intestines.

:primarily causes ulcerations of the small and large intestines, then affect the digestive tract.

Crohn's disease and ulcerative colitis: inflammatory bowel disease (IBD).

 Abdominal pain, diarrhea, vomiting, fever and weight loss are symptoms of Crohn's disease.

Crohn's disease can be associated with reddish, tender skin nodules, and inflammation of the joints, spine, eyes, and liver.

Treatment of Crohn's disease includes drugs for suppressing inflammation or the immune system, antibiotics, and surgery.

Crohn's disease tends to be more common in relatives of patients with Crohn's disease.




Graves' Disease

Graves' disease is one of the most common of all thyroid problems. 

:cause of hyperthyroidism (over activity of the thyroid gland ).

: It is due to an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormone. 

common symptom: Anxiety, Breast enlargement in men, Difficulty concentrating, Double vision, Eyeballs that stick out Eye irritation and tearing,Fatigue.

Treatment : controlling your overactive thyroid.



Ankylosing spondylitis

 inflammatory disease , cause some of the vertebrae in spine to fuse together. 
: makes the spine less flexible( hunched-forward posture).
 If ribs are affected, it may be difficult to breathe deeply.

:affects men more often than women.

people who have a gene called HLA-B27 are at significantly increased risk of developing ankylosing spondylitis.

common symptoms : pain and stiffness in  lower back and hips.

Treatment: use of medications to reduce inflammation and suppress immunity to stop progression of the disease.

Saturday, March 22, 2014

Celiac disease



Celiac disease

chronic digestive disease with both a environmental
and genetic component that damage small intestinal mucosal.

Celiac disease:  1% of American population 
:cannot tolerate gluten.Gluten have two major protein types: gliadins, glutenins.
 They have resistant to complete digest by human intestine enzymes.

They eat food containing gluten, their immune system over activity cause inflammation:
destroy villi ,malnutrition



Other symptoms: fatigue, anemia, arthritis, osteoporosis , irritability, constipation, miscarriage and, dermatitis.

CD is associated with the major histocompatibility complex (MHC) class II alleles: HLA-DQ2,HLA-DQ8

Only effective treatment :Gluten- free diet.