Ikaros Transcription Factor

Ikaros 

Ikaros positively or negatively controls gene transcription. 

Ikaros is zinc finger transcription 

factor that has a critical regulator of hematopoiesis. 

Furthermore, Ikaros is a critical tumor suppressor
and has a critical regulator of B cell lymphopoiesis and function.  
They express in anterior pituitary gland.


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Ikaros controls multiple levels of B cell lymphopoiesis and function

MacLean Sellars, Philippe Kastner and Susan Chan.Ikaros in B cell development and function.World J Biol Chem. 2011 June 26; 2(6): 132-139.