Thursday, January 23, 2014

Rheumatoid Arthritis




Rheumatoid Arthritis (RA)

 

          RA is an autoimmune disease that causes chronic inflammation of the joints.



  Autoimmune diseases are illnesses that occur when the body's tissues are mistakenly attacked by their own immune system.



  Patients with autoimmune diseases have antibodies in their blood that target their own body tissues,and cause inflammation.  


  The cause of rheumatoid arthritis:  may be genetically inherited.

 

  Immune system promote inflammation in the joints and occasionally other
 tissues of the body.  lymphocytes, are activated and chemical messengers
 (cytokines, such as tumor necrosis factor/TNF, interleukin-1/IL-1, 
and interleukin-6/IL-6) are expressed in the inflamed areas.


Environmental factors like smoking also seem to play some role in causing rheumatoid arthritis. 

 


I was in my car and listening to the radio that had a healthy program about RA patients and their special diet. My aunt has Rheumatoid Arthritis for more than 15 years. I believe that one of the most important factor that she is alive now , is her positive
mind!!!!!





Ames R. O'Dell, M.D., Ted R. Mikuls, M.D.Therapies for Active Rheumatoid Arthritis after Methotrexate FailureN Engl J Med 2013; 369:307-318.


 Violeta Romero,Justyna Fert-Bober,mmune-Mediated Pore-Forming Pathways Induce Cellular Hypercitrullination and Generate Citrullinated Autoantigens in Rheumatoid Arthritis.Sci Transl MedVol. 5, Issue 209, p. 209ra150


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